PROTON PUMP FUNCTION IN GASTRIC ACID SECRETION

The proton pump contributes a critical role for gastric acid {secretion|. The pump is an integral membrane protein found at the apical membrane of parietal cells within the stomach lining. It facilitates the active movement of protons (H+) from the cytoplasm of parietal cells into the gastric lumen, leading to the lowering of the stomach contents.